MMP – Drug Microinfusion into the Scalp

What Is MMP®

MMP® (Microinfusão de Medicamentos na Pele) is an intradermal microinfusion technique that uses professional microneedling devices to deliver medications directly into the skin in a uniform, controlled, and highly precise manner.

Initially developed for the treatment of idiopathic guttate hypomelanosis, the method quickly found application in the management of alopecias, particularly:

• androgenetic alopecia
• alopecia areata
• telogen effluvium

Today, it is one of the most widely used procedures in trichology, with thousands of treatments performed every month in Brazil, where the technique was originally codified and disseminated.

How It Works

MMP^® uses extremely fine microneedles that, moving at high speed, deliver the medication directly into the dermis, at the level of the hair follicle.

The technique allows:

• homogeneous microinjections across the entire treatment area
• control of needle depth and speed
• optimization of the active ingredient’s bioavailability
• reduction of the total amount of medication required
• fewer local side effects
• greater efficiency compared to traditional intralesional injections

The procedure is generally well tolerated.

To date, no serious adverse effects have been reported.

Why It Is Useful in Androgenetic Alopecia

In androgenetic alopecia, the medication must reach the follicle at adequate concentrations to inhibit DHT activity and support bulb function.

MMP^® allows clinicians to:

• maximize local effectiveness
• almost completely reduce systemic exposure
• limit the side effects typically associated with oral treatments

The most significant evidence comes from the study by García-Hernández et al., J Cosmet Dermatol (2022), which showed:

• 70% clinical improvement in patients treated with microinfusion
• 30% in patients undergoing conventional topical therapy

Results Observed at Dermacademy

Based on our clinical experience acquired during the months of applying this technique, the most frequent benefits include:

• reduction in hair shedding already within the first weeks
• increase in hair shaft diameter
• greater density in thinning areas
• more homogeneous regrowth
• improvement in the overall quality of the scalp

The technique integrates easily both into pharmacological pathways and regenerative treatment programs.

The Dermacademy Method

Before proposing MMP^®, each patient undergoes a complete trichological evaluation, which may include:

• specialist consultation
• digital trichoscopy
• evaluation of scalp inflammation
• analysis of any ongoing therapies

Microinfusion is prescribed only when indicated and is always personalized according to the clinical situation.

The treatment is performed by physicians directly trained on the MMP® protocol by Dr. Rivetti, collaborator of the inventor of the method, Dr. Arbache:

Dr. Giovanni Menchini

Dr. Fabrizio Lombardo

Dr. Chiara Scacciati

Treatment Protocol

Session duration: approximately 20 minutes
Sensations during the procedure: mild burning or temporary discomfort
After treatment: mild redness or itching, self-limiting within 24 hours
Return to normal activities: immediate

The frequency of treatment is determined by the specialist according to the clinical picture and any ongoing therapies.

Cost of Therapy

Cost per session: 220 euros (VAT excluded)

Who It Is Recommended For

MMP^® may be indicated in cases of:

• early or intermediate androgenetic alopecia
• diffuse thinning
• persistent telogen effluvium
• intolerance or poor response to topical treatments
• the need to reduce exposure to systemic medications

Why Choose Dermacademy Institute

MMP^® is a new method of drug delivery that, when integrated into a structured clinical pathway, allows results to be optimized.

At the Dermacademy Institute, the treatment is part of an integrated approach combining:

• precise diagnosis
• selection of the appropriate medications and concentrations
• continuous monitoring
• personalization of the therapeutic pathway

Our goal is not to “hide the problem,” but to intervene with method, clinical evidence, and therapeutic continuity.